Not to step on any toes here but it seems as though you all may not be familiar with the meds. Stalevo has sinemet in it. When you take it you need to lower your regular sinemet to compensate. That's why you get the inconsistencies, dyskinesia, etc; I'd guess that you prob take a stalevo then get dyskinesia, miss a sinemet dose because you're way too on then crash when the stalevo wears out which is in between the sinemet doseages, etc. The agonists were too inconsistent for me. I've got enough to just keep up not to have to worry about off times etc. I think you would do better to find out how long after taking 1 sinemet you go "on" and how long it lasts. Take as little as possible and stay away from the agonists, they are too much up and down for me. When you find what works for you don't let anyone ???? with it.