Quote:
Originally Posted by wondergirl
Meaning that the ACTN3 thing means I don't have MG for sure? Or the opposite or neither? I saw something about this but don't understand.
23andme is something many people get done, it's promoted to individuals, I did it out of curiosity, some people said it was interesting and worth it.
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how and why autoantibodies are produced is not yet fully understood. but, we do know that there are certain proteins that may be more prone to be recognized as non-self, by the immune system.
so, production of autoantibodies is probably a combination of the genetics of the individual's immune system, combined with the genetics of the proteins to which those antibodies are directed.
I can't comment on if you do or you don't have myasthenia, according to my oppinion, as I have no data to base this on. eg-what your symptoms are, what tests you had, etc.
all I can say is that it is becoming more and more clear that myasthenia is not just one disease, in which there is an abnormality of the acetyl-choline receptor and abnormal electrical signaling in the neuromuscular junction, but it is much more complex then that.
alice