I have had much less muscle pain since starting the ribose. I have more stamina too. This was slow to materialize but it is helping me nicely. Ribose is part of the adenosine molecule that is involved in energy production in the mitochondria.

I have to wonder if the PN IS more commonly connected to mitochondrial functions, than we all realized? We know mito issues occur in toxic and drug induced PNs. It is suspected in diabetic induced. It might turn out with more research that mito issues are involved in all of us, to some extent.

I used to think, it was because we walk differently and favor certain muscles we wouldn't normally do, and those fatigue?

Chiropractors explain alot of pain this way, as stress on systems trying to make do with a "problem".