I was given celebrex for my arthritis, by a rheumatologist. I asked her about my at risk cardiac profile and arrhythmias...."Oh it's fine".

Later, my cardiologist said, "I would not take it if I were you".....so, one doc may say it is fine, another not.

I have kidney issues, exactly what we are discussing here, the low bicarb. Mine isn't due to medication as far as I know, because I am not on that much....however, I would not risk your precious kidney function on this drug, when you can get the same effect from other medication.

Also, I read your history and was wondering if they ever tested you for autoimmune diseases, and things such as Raynauds? I may have missed this in another post of yours, but, I figured you could tell me quicker than I would find it.