Diagnosed in 2007, have had what seems to be exacerbation's: (starts with numb and tingling in leg then hands and strange headaches and confusion, feeling awful)each late spring since. I had an infusion the first year and this time I took the pills, I caught this one early because I had been there last year. Is this what to expect even while on the disease modifying medications once a week? I had read that some people on the meds do not have relapses for years.Should I talk to my Dr. about changing medications? This HOT summer is doing me in. I'm stuck inside with the 101+ temps outside, I had been person who loved the outdoors, now it brings on the above.