from Psychiatric Times
Bone Mass Density Loss and Antidepressants...
By James M. Ellison, MD, MPH
October 1, 2008
http://www.psychiatrictimes.com/disp.../10168/1336555
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I could locate no study that addresses serotonin norepinephrine reuptake inhibitor (SNRI) effects on BMD, although the SNRIs’ serotonergic effects certainly raise the possibility of a similar BMD reduction risk.
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also - this explains it in a more similar fashion to what i originally read.
CHANGING THE PICTURE IN DEPRESSION... (
MS Word document)
Sinan Duzyurek, MD
July 18, 2009
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Too high intercellular concentrations of serotonin outside the bone cells (e.g., due to lurking SSRI molecules) preferentially stimulate osteoclasts, which degrade bone. Thus, patients on SSRIs and SNRIs are at increased risk for fractures, and women have double the incidence of osteoporosis.
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~ waves ~