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Old 07-30-2010, 01:29 AM
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Ronhutton Ronhutton is offline
In Remembrance
 
Join Date: Aug 2006
Location: Village of Selling, in County of Kent, UK.
Posts: 693
15 yr Member
Ronhutton Ronhutton is offline
In Remembrance
Ronhutton's Avatar
 
Join Date: Aug 2006
Location: Village of Selling, in County of Kent, UK.
Posts: 693
15 yr Member
Default PD Research

Hi Robert,
There are other groups doing research into objective measurement of symptoms, maybe you could combine with them. see
http://www.sage-hindawi.com/journals...10/760196.html
for example.

Objective Quantification of Neuromotor Symptoms in Parkinson's Disease: Implementation of a Portable, Computerized Measurement Tool
Spyridon Papapetropoulos,1 Heather L. Katzen,1 Blake K. Scanlon,2,3 Alexandra Guevara,1 Carlos Singer,1 and Bonnie E. Levin1,4
1Department of Neurology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
2Sierra-Pacific Mental Illness Research, Education, and Clinical Center, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
3Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
4Department of Psychology, University of Miami, Coral Gables, FL 33124, USA


Received 6 August 2009; Revised 13 April 2010; Accepted 4 May 2010

Academic Editor: Fabrizio Stocchi

Copyright © 2010 Spyridon Papapetropoulos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract
Quantification of neuromotor symptoms with device-based measures provides a useful supplement to clinical evaluation. Research using the CATSYS has established its utility as a computerized measurement system to quantify neuromotor function. The primary objective of this study is to provide technical guidance on the use of the CATSYS in Parkinson's disease (PD). Forty-four patients with idiopathic PD and 28 healthy controls were prospectively recruited and evaluated with CATSYS, a portable, Windows-based system consisting of a data logger and four different sensors (tremor pen, touch recording plate, reaction time handle, and force plate for balance recording) for quantification of neuromotor functions. CATSYS discriminated between PD and controls on measurements of rest/postural tremor, pronation/supination, finger tapping, simple reaction time, and postural sway intensity and velocity. CATSYS measurements using the proposed test battery were associated with relevant clinician-rated Unified Parkinson's disease rating scale (UPDRS) items assessing tremor and bradykinesia. More work is warranted to establish CATSYS as a diagnostic/monitoring instrument in movement disorders using the proposed technical approaches.
Ron
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