responded the same to regular mirapex/requip, requip incapacitated me, could barely tolerate .125mg mirapex so settled on sinemet. will be very interested in your extended release mirapex experience.

there's this trial:
A Multicenter, Randomized, Double-Blind,Placebo-Controlled, 5-Arm, Parallel-Group Trial To Assess Rotigotine Transdermal System Dose Response In Subjects With Advanced-Stage Parkinson's Disease

Description
The primary objective of this trial is to show rotigotine dose response (at 2, 4, 6, or 8mg/24h) in subjects with advanced-stage Parkinson's disease. A secondary objective is to demonstrate the safety and tolerability of rotigotine at these doses.

Currently Enrolling

Who Can Participate?
Patients who are at least 30 years of age and with a diagnosis of idiopathic Parkinson's disease, of more than 3 years duration, as defined by the cardinal sign, bradykinesia, plus the presence of at least 1 of the following: resting tremor, rigidity, impairment of postural reflexes, and without any other known or suspected cause of Parkinsonism.

Investigator:
Alida Griffith, MD

For More Information:
Marsha Merrick 425.899.3115 MGMerrick@evergreenhealthcare.org
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looked up side affects for this agonist and skipped even applying.