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Old 08-05-2010, 11:04 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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Hi, I am still on vacation, but saw this post ...so briefly...

There are two types of "treatment" available. One is symptomatic treatment only (which most PN drugs do except for IVIG) and actual intervention treatment like the supplements which promote healing. IVIG remains the most useful treatment for reversing some PN.

The SSRI antidepressants work centrally in the brain to suppress some of the chronic pain loop that exists in chronic pain states. They do nothing for the actual healing of PN and do not prevent progression at the peripheral level.

There has been one study showing that amitriptyline may actually stimulate regrowth of peripheral nerves...so that antidepressant is distinct from the SSRIs.
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