Hello, I have been on MS Contain and Kadian at different times. I receive no high eithor, and was told these meds go to the pain receptors, and there is none left over to get high on. I have also lowered the amount I take via drs. orders and have not had trouble. I went down by half for awhile after my spinal epidurals. I only got a little sweating, and it wasn't bad.