Can you actually skip sinemet? When it wears off are you worse than you were before you started it?

Also I have no drive or motivation which I imagine is due to lack of dopamine - will sinemet help that?[/QUOTE]


P.S. i feel a general overall improvement and as yet the on/off boundary pretty fuzzy so the answer (so far) to your second question above is no! i am definitely better off overall.

answer to the third question is a big YES it does help with motivation however it doesn't change the fact that we are all subject to cycles and cycles within cycles

md