Hi there davelikesfish, and welcome to NeuroTalk.

Sorry that I can't answer any of your questions, but I did see that you were enquiring about LDN and there is a thread on our multiple Sclerosis Forum that's dedicated to LDN.

Although you're enquiring for totally different reasons, I wondered if some of the long term LDN users on that forum might be able to assist in your enquiries. Many have been taking LDN for some time, so don't be afraid to ask them about it.

Here's the link for you:
http://neurotalk.psychcentral.com/thread71392.html