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Old 08-20-2010, 11:11 AM
Christy Christy is offline
Junior Member
 
Join Date: May 2009
Location: Atlanta, GA
Posts: 17
15 yr Member
Christy Christy is offline
Junior Member
 
Join Date: May 2009
Location: Atlanta, GA
Posts: 17
15 yr Member
Smirk Good Afternoon

This might be of interest :

Concentric-needle single-fiber electromyography for the diagnosis of myasthenia gravis.
Benatar M, Hammad M, Doss-Riney H.
Department of Neurology, Emory University School of Medicine, 1365A Clifton Road NE, Atlanta, Georgia 30322, USA.
Abstract
The goal of this study was to estimate the accuracy of concentric-needle single-fiber electromyography (CN-SFEMG) for the diagnosis of myasthenia gravis (MG). A consecutive series of patients referred for CN-SFEMG was evaluated by an investigator blinded to the results of CN-SFEMG in order to determine the presence or absence of MG using an independent reference standard. Sensitivity, specificity, predictive values, and likelihood ratios were calculated. The study population included 51 patients (21 with MG). CN-SFEMG was normal in 34 patients (67%) and abnormal in 17 (33%). The sensitivity of CN-SFEMG for the diagnosis of MG was 0.67 and the specificity was 0.96. The positive likelihood ratio was 16.8 and the negative likelihood ratio was 0.34. The positive and negative predictive values were 0.93 and 0.76, respectively. These results indicate that CN-SFEMG showing abnormal jiggle is extremely useful for confirming the diagnosis of MG, but that CN-SFEMG showing normal jiggle has limited utility in excluding the diagnosis.

Also

This week from
Neurology® Podcast there is a podcast on MuSK antibodies of interest.


“…………………. In the next part of the podcast Dr. Beau Bruce interviews Dr. Donald Sanders about MuSK antibodies ………………………………..........”

It starts about ½ way into the Podcast.

www.aan.com/rss/?event=feed&channel=1


Hope this helps.
Christy,
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