I don't know if I've even had all the tests you mentioned, but I have SFSN diagnosed by skin punch biopsy.

Just received the very last of the bloodwork tests after having many on this hunt for a cause over the months, and they were all normal. Including intrinsic AB block (determine if B12 is being absorbed). Plus had these during the past months:

1. Acetylcarnitine/carnitine

2. COQ10 total
COQ10 Reduc
COQ10 Oxid
COQ10 % Reduced
COQ10: Chol

3. ESR by Westergren

4. Serum B12

5. Vitamin B6

6. Vitamin D

7. Vitamin D3

8. Vitamin B1

9. Catecholamines:
Epinephrine (by plasma)
Norepinephrine (by plasma)
Dopamine (by plasma)

10. Folate, TSH, T4 free/free thyrox

11. Monoclonal Prot. Bld.

12. Complete Metabolic

13. ANA Panel Blood Screen

14. C-reactive protein

15. ACE/Angiotensin Bld.

16. Anti-ENA ID

17. HU AUTOANTIBODY Bld.

18. SYPHILIS IGG WITH CONF. (sqsyphgx)

19. Cryoglobulin Bl.

20. LYME

21. Rheumatoid Factor BL.

22. Anti-Neutro Cyto AB

23. Vitamin E/Tocopherol

24. Anti GM1 Triad

25. HIV RNA viral load (not suspicious for this - just did it because it can cause neuropathy)

26. LUMBAR PUNCTURE

27. CT Chest w/contrast - normal

28. Neoplastic panel to Mayo Clinic to rule out malignancy anywhere.

Everything normal except for slight hypothyroidism and the SFSN by biopsy.

Today, I reached the probable end of the diagnostics trail. Will have to adjust to this, knowing no cause was found.

Hope a cause is found for you!

Best wishes,

Sheltiemom