I have been taking it since Jan started off at half a 0.25mg once a day and then it was increased up to 1.5mg 3 times a day in a 2 week period. i have segmental spinal myoclonus (quad and hamstring nerve root damage from an epidural post op pain control) the local docs (PCP and neuro) have been throwing pills at it left and right since it started jerking and at times "flopping around like a fish out of water)basically non stop back in Jan. My MDN wants me off the mirapex, had also been on keppra but off that now. It was suggested that I post this over here since more likely to find someone who has come off it here than in the movement disorder forum.