Now I am really concerned. Why aree these researchers just now finding this out? Several of us on the old braintalk forum discussed the mode of action of at least 4 classes of chemicals composed of many different substances, which targeted specific cellular processes. There were/are oxidaive phosphorylation inhibitors, uncouplers, those that make the cell membrane more permeable, and those that interrupt mitochondrial function by becoming out-of-place electron acceptors. All 4 of these processes, if interrupted can lead to neuron death and parkinson's disease or other neurological disorders. Professor Illingworth of the University of Leeds clearly points this out. Our own government found this out during their study of pesticides to see which ones could be used in concentrated form for biological warfare...and that was before and during WW2. There is even a database into which a chemical formula can be dumped in order to ascertain which category it fits. What disease can I get from my blood boiling?
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There are tens of thousands of synthetic industrial chemicals, pesticides, metals, and other substances for which toxicological information is limited or nonexistent. By identifying a molecular target that is shared by toxic substances, all with very different chemical compositions, this discovery may give scientists a method to rapidly evaluate compounds to determine whether or not they pose a potential health threat.
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michael (excuse-my-rant) b.