Quote:
Originally Posted by RLSmi
is the name given in an article I read in Nature in 1997 for what was thought to be the major active endocannabanoid. There are very small amounts of related compounds in chocolate, according to the same article. As I recall, the name is derived from the Indian (Sanskrit?) word for "bliss", pronounced [U]ananda[U].
Anandamine is a relatively simple derivative of a fatty acid and bears little structural similarity to THC, the main active ingredient in [I]Cannabis sativa.
I know nothing about the biosynthetic pathway for synthesis and breakdown of any of the endocannabanoids.
Robert
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One thing I noticed in RLSmi's post was that it is derived from a fatty acid. Since I had just posted regarding the purported value of essential fatty acids in the control of dyskinesias, that got me to wondering about the possible connections. Any thoughts from the chemistry involved?
-Rick