Hi Leanne,
These tests are both negative, but please do not consider it the end of the story.

You can definitely have gluten sensitivity causing serious health problems without testing positive for celiac disease via the above antibody tests, and without a positive intestinal biopsy. The blood tests mentioned above represent a very bare bones version of the complete celiac panel, for one thing.

Read more about diagnostic testing here:
https://sites.google.com/site/jccglu...gnostictesting
https://sites.google.com/site/jccglu...ndstooltesting

Read more about gluten sensitivity vs. celiac disease here:
https://sites.google.com/site/jccglu...sceliacdisease


You have several options:

1) Seek further testing.

You could request the antigliadin (AGA) IgA and IgG test. It is a much more sensitive test for identifying gluten sensitivity. Be sure it is the antigliadin AGA and NOT the deamidated gliadin DGP test that is ordered. Request a total IgA testto rule out IgA deficiency.

or

Test through Enterolab which is a stool test that looks for antibodies to gluten in the stool rather than the blood. It is considered a much more sensitive test for diagnosing gluten sensitivity. Enterolab testing cannot diagnose celiac disease. Stool testing is still considered an "alternative" test, but many physicians are beginning to use this test.


2) Begin a gluten free dietary trial and see if you enjoy any symptomatic improvement.

I'm not sure what your symptoms are, but you should know that about half of those with gluten sensitivity also have casein sensitivity. Many people have problems with other grains, too, not just wheat, barley and rye. If you opt to go with a dietary trial you might want to start with a no grain, no dairy diet for a couple of months and see if you improve. There is tons of information on a Paleolithic Diet on the Internet. It is tricky, because if you have trouble with several foods, but only remove gluten, you may not see the improvement.

3) You could have some food allergy testing done.

Not only traditional IgE food allergy testing but also delayed (IgG) food allergy testing. This can help to pinpoint other foods you may need to eliminate. I've known many people who had good results removing foods determined by IgG food allergy testing. There are several labs that do this testing.. .some are listed on the right bar here:
https://sites.google.com/site/jccglutenfree/foodallergy


You haven't mentioned what your symptoms are but food sensitivity, whether gluten sensitivity alone, or multiple food sensitivities, can wreak havoc on your health even in the absence of celiac disease. Don't give up on this avenue of "food" being culprit for your health problems until you've taken a more thorough look and done some dietary trials.

Hope this helps!