I am trying to figure this out. According to scientists, too many polyamines result in increased excitoxicity and result in us losing dopaminergic neurons.
Yet, a PD drug, Selegiline, long purported to be neuroprotective actually fosters proliferation of polyamines. In other words, it may be more harmful, than good? Or does something else happen that balances out or cancels out the harmful effect of the polyamines?

Confusing to say the least...

Laura