It takes time to find the right mix of medications. Try to deal with the symptoms one at a time until they are controllable. This means you need to learn your triggers as well and avoid them. Try to start medications one at a time when you can so you know which one is causing the bad side effects.

Hang in there. Amputation is a desparation play. If it worked it would be the first thing most of us would do. It has only about a 10% success rate and most cases are made worse.