I've been on it since June, 200 mg. day, am supposed to add another 100 mgs but hesitate because of weight gain!! I've gained 15 lbs and I eat very little most days. I seem to put it on in the "belly and behind" first, so I'm already up 2 pant sizes - in 3 months! At this rate, am afraid to think what size I will be by end of the year, without adding an extra 100 mg/day

I was REALLY hoping the weight gain problem was one of the side effects of Neurontin they had "fixed" when they developed Lyrica. Otherwise, I don't notice any problems with it, and it DOES help with the nerve pain. I take Cymbalta as well for depression and nerve pain and the combo works better than anything else for me so far.

I'm also a little hesitant to go to higher doses of Lyrica because at higher doses of Neurontin I had problems with blood in the urine, I think it was affecting the kidneys. Although very rare, there had been some incidence of this in the clinical trials (for Neurontin, not Lyrica). Anyway, I was taken off Neurontin at that point, which I understood, and agreed with, but I soon learned how much the Neurontin had been helping me, and haven't found anything since that is as effective. I was glad to hear of Lyrica's development and lower dosage and side effect profile, and hope the problem doesn't reappear and take away this source of relief!

beth