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Old 10-12-2010, 08:46 PM
lurkingforacure lurkingforacure is offline
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Join Date: Feb 2008
Posts: 1,485
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lurkingforacure lurkingforacure is offline
Senior Member
 
Join Date: Feb 2008
Posts: 1,485
15 yr Member
Default that also works for us

Quote:
Originally Posted by made it up View Post
Peony,
I've found dystonia to be very responsive to levodopa.
Perhaps if you try less sinemet at a time more frequently and still in total for 24hrs have amt neuro prescribed?
That and or try adding something like comtan to lengthen your ons and therefore reduce the dystonia?
Cheers
We do this also, it means taking pills every two hours and having to split pills as well, but it works better than anything we've tried, and as our drug-savvy former neuro pointed out, taking smaller doses of levodopa throughout the day is much better for the system than the larger doses which tend to cause the spikes we all try to avoid. The problem, just to forewarn you, is that sometimes that smaller dose is really not enough to get things going and stay going. We've played with taking a whole sinemet in the morning, then half throughout the rest of the day (not so good), and variations on that theme, but honestly, so far the best we've been able to come up with is the half a sinemet every two hours. It's not great, and a lot of days are pretty crappy, just being honest, but we are trying to avoid starting down the dyskenesia road as long as possible. Don't be afraid to experiment with the dosing as long as you tell your doc what you are doing, and you might want to ask him/her what his recommended max of each drug he's scripted for you is.
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