Thread: PGC-1 alpha
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Old 10-14-2010, 07:16 AM
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reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
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reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default PGC-1 alpha

This is getting more and more interesting and it deserves its own thread-

The story thus far, in part, is that low levels of PGC-1a are linked to Alzheimer's and diabetes. More and more that list is expanding to include PD. PGC-1a can be increased by intake of fatty acids. Those fatty acids are particularly plentiful in coconut oil. You may remember earlier discussion here on Dr. Mary Newport and her husband and their success using coconut oil in combating his early-onset Alzheimer's.

As to what is going on, it is too soon to say. It could be that high glucose levels and/or insulin resistance is the link. It could also be transfats in our diets or a dozen other things.

Time will tell, but time is a precious commodity and I don't have as much of it as I would like. So, as of two days ago, I have jumped on the coconut oil band wagon. My initial reaction is "Damn! This stuff seems to be working!" Placebo? Who knows at this point.

I will, of course, post my observations, but my immediate one was that I was seriously over medicated and have begun to cut back. Second, yesterday I put in a good three hours swapping two washing machines around by myself without going off. Finally, I got up this morning and couldn't find my stick. It wasn't in its usual place at my bedside. I had gone to bed without needing it for the first time in months.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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