Augie, it is just a minor technicality but I thought I would mention that the 125 mcg amount that you make reference to would be the amount (I presume) that is released into your system every hour (as opposed to every 72 hours as suggested in your post), when the medication is delivered at the maximum rate for which the particular patch dosage is intended. The patches for many people tend to release a lesser amount on the third day than that which is indicated on the packaging, and for that reason, some doctors will prescribe the patches to be replaced every other day (ie. every 48 hours) instead of every three days (72 hours).