I should have mentioned in my prior post that the more consistent release of medication for some people over a two day period took place with the original Duragesic patch design which held the medication as a liquid in a "pouch" section, while the delivery system has since been improved so as to hold the fentanyl within the membranes of a matrix-like film for better, more even release. This newer version might in fact release the contents more consistently over a three day period (though I am not certain if that is in fact the case).