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Old 10-19-2010, 04:02 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Many of the trials used IV form.

When you get up there in dose, there are side effects.

Dizziness is the most common. It is absorbed well orally however.

If you go thru that process of compounding...see if you can get a sustained action form while you are at it. That would give better pain results than having to do several oral doses daily.

This study used 45mg:
http://www.ncbi.nlm.nih.gov/pubmed/19198708

Metabolic problems in dosing in a poor metabolizer patient, including interaction with amitriptyline:
http://www.ncbi.nlm.nih.gov/pubmed/18359183

Go to PubMed and type in "dextromethorphan pain" and there are 206 hits... many saying not effective. And some saying more effective in males than females. And some metabolic liver enzyme warnings.
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SandyS (10-19-2010)