My neurologist says he's never heard of this.

Here is the deal:I wake up slow and stiff but can walk ok; I take my Sinement 25/100 and Mirapex .5 and in about 20 minutes I moves pretty good - for about 2 -3 hours, then I get kind of slowed down and stiff and take my second dose - after 20 minutes of so, I just kind of freeze, can't move. Hurts to try to walk. This lasts for up to an hour, then I can walk and move normally for about 1or 2 hours - after which I repeat the cycle until bedtime.

I tryed to explain this to my doc who responded by cutting me back from 5 doses of meds a day to 4, which was not helpful.

Has anyone else had this bad reaction to their medications followed by okay respoonse an hour later? I would really appreciate any thoughts anyone has; this has chopped my day up so I'm almost housebound.

Thanks so much for your help.

Sasha