Quote:
Originally Posted by reverett123
We are leaving neurology behind and entering the world of endocrinology. I am convinced that that is where PD lives. Yes, we have damage to particular parts of the brain, but the causes of that damage come from here as well as the immune system. Motor symptoms result from the latter's inflammatory response. Non-motor symptoms, however, are a child of the endocrine and stress.
Long neglected because neurology didn't consider it important, the endocrine system is all about stress and emotions. We all know what an effect these have on our symptoms, but we are only now starting to wonder what they were doing to us during those "pre-clinical" decades prior to that first tremor.
There is much here to lean.
-Rick
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Ran across this phenomenon known as "apathetic thyrotoxicosis". In these case studies, people have symptoms opposite of the classic hyperthroid presentation. Note all patients express a sense of profound weakness; one could barely walk and another bedridden. It is noted that dopamine regulation of thyroid hormone levels plays a role.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955902/