Dejibo,

It all depends on how you feel before, during and after plus what can you "SAFELY" accomplish in the traveling? I don't know how far you are talking so I really can't relate.

For my wife and I, if it is over 2+ hours, we always fly and pay extra for a nonstop. The key is to fly at off peak times, use rental car and hotel discounts. The whole objective is to save your energy to enjoy your family not getting to and from the celebration.

Depending how far along you are with the disease progression, not to mention the side effects of meds, possibly a long drive is no longer reasonable or safe. The term, "under the influence" includes medications Rx'd or not. Your travel time is the most expensive per hourly investment of both time and money. Not to mention energy allocation.

To me, flying "IS" the only mode of travel to accomplish all of the above.