View Single Post
Old 10-26-2010, 06:58 AM
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default If you have all-over body symptoms--

--whatever you have is not length-dependent.

Length-dependent refers to those neuropathies, often ischemic (circulatory) or metabolic in nature, in which the longests nerves are compromised first, usually at the very ends. That is because in these neuropathies, the nerves "die-back"; that is, due to the body's inability to transport sufficient nutrients/oxygen to the very ends of the nerves (farthest from the body's circulatory center), and/or to transport metabolic wastes away from those areas, the nerves begin to show problems at their very tips first.

Small-fiber diabetic neuropathy is the classic type for this process, which is why diabetics tend to get nerve problems first in their toes, then their feet, then their fingertips, and so on--the "stocking and glove" distribution.

It is, of course, possible to have small-fiber neuropathy that is not length dependent, as well as large-fiber neuropathy that isn't. It very much depends on cause. A number of autoimmune and toxic conditions have effects that are more global.
glenntaj is offline   Reply With QuoteReply With Quote