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In Remembrance
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Join Date: Aug 2006
Posts: 3,772
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In Remembrance
Join Date: Aug 2006
Posts: 3,772
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the nose knows
What do the nose and stomach, the two places where PD first shows up as Lewy Bodies, have in common?
1- they are places where the mucus membranes interface with the external world via inhalation and post-nasal drip
2- they are near major CNS components- the olfactory bulb and the enteric nervous system aka as the "second brain"
3- both components have direct routes to the brain via the olfactory and vagus nerves.
4- both routes bypass the BBB
What else?
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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