Hi Lisa and welcome to NeuroTalk.

I'm sorry that the MS Meds arent working for you so far.. That's a long time to be shooting yourself for nil.

I don't have any suggestions, other than LDN, because It has help me to stay stable, when the DMDs did not.

I hadn't tried Tusabri and for some, it works and seems to be a good thing, but for some, it does not work at all and then of course, there is that looming risk of contracting PML.

I hope you stay right here and work it out with us. There are plenty of people here on one DMD or the other, who will tell you of their experience. We will support you, whatever method of treatment you choose.