Hmmm...the things that are really tough on me are cold (this is the absolute worst thing...even a light breeze of cool air is torture), too much movement, too little movement, putting too much weight on my foot (where my RSD is), stress, any sort of pressure on the wrong spot (can't wear most of my gym shoes because there is too much padding and I just can't take it...can only wear one pair where all the padding is worn away...and even just wearing socks hurts), and sometimes it just plain hurts worse and I can't pinpoint what has caused it. But the things I listed are the ones that I know of that send me into an entirely different level of pain.