Hi,

I ran across this article and found it interesting. Even if only four people...means others are experiencing it too. The "it" is a prolonged period of "on" time or time where patient feels near normal long after a medical dosage has worn off. This is like an hour after wear off meaning this entire experience is highly unusual. I am wondering if this isn't further indication that all of our cells are on an inevitable path of self-destruction; that in fact, many of our cells are merely impaired or "stuck" somehow? Has anyone experienced anything like this? This also serves to highlight how hard it is to study advanced PD when medication masks everything

Novel pattern of levodopa-related motor fluctuations: ‘Paradoxical’ on

-Laura