Hello All,

Thank you for the replies and the concerns. I spoke to my mother on the phone this evening around 5:00 PM EST to see how her evening last night and how her day went today. She took her 9:30 PM CR pill last night and went to sleep around 11:30 PM. She woke this morning and took her 6:30 AM dosage of IR around 6:20 AM. When I asked her how she felt this morning, she said that she felt she was a bit more "alert" this morning than usual. When I asked her how she felt in general, she mentioned that there were a few times throughout the day where she thought to herself "I do not feel too bad right now", but also commented that her mobility was still slow and rigid. I personally physically heard a bit of improvement in the amplitude and clarity (less mumbling) in her voice around 5:00 PM EST this evening. We spoke on the phone for about 25 minutes which means she was quite talkative. She comosed an e-mail to me at 10:14 AM this morning which had virtually no spelling mistakes or typos. In the past, due to the limited dexterirty in her hands, her e-mail compositions would have spelling mistakes (because I know that spell check would confuse her) and typos because she is apprehensive to use the backspace key to go back and make corrections. I noted all of the aforementioned in my journal and also conveyed our (the forum) most recent conversations last evening. I really would like to speak to the neuro more in depth with regard to the CD/LD versus Sinement. Note that I have asked 2 neuros the same question with regards to brand name versus generic and both (one being the specialist from last Friday) indicated that there is no difference, however, after speaking to individuals with personal stories to tell, I would like to push the subject matter at hand a little further.

TG - I do see your point with regards to my mother realizing benefits from the CD/LD at one point in time which most likely means she has the PD. That exact thought has crossed my mind, my only concern is that when I read some of those scary diseases I see other factors in common such as the majority of patients with the atypical forms typically do not have tremors. My mother, at least at this point, does not have tremors. The other big sign is the mention of urinary and bowel incontinence. My mother has had the urinary incontinence for quite some time, and I have been told that within the past 2 weeks she has been having issues with her bowels. Is incontinence an issue with PD?

Best Regards,

Matthew R. Smith