I think the beta blockers can be more problematic. Some people get a myotonia from them, and the cold extremity thing they cause also is bad for the nerve endings.
Sulfa and also drugs similar like the diuretics and Celebrex also cause photosensitivity reactions when skin is exposed to UV sunlight. I suspect they are difficult for this reason too. They must go into the skin or their metabolites or whatever.
The allergic reactions to sulfa drugs or drugs with that S group on them, affect the skin dramatically, and in some cases destroy nerves. There used to be a 24hr once a day sulfa called Kynex many years ago that caused deafness and severe allergic reactions. It was taken off the market.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
************************************
.
Weezie looking at petunias 8.25.2017
****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.