I know I'm late to the discussion, but I wanted to chime in here. Mirtazapine has been fantastic in terms of controlling my tremors. Though I can't help but wonder whether the drug's effects are a little "indirect." The drug helps me sleep at night, quashes nagging anxiety and nervousness - simply put, makes me feel calm all over, which contributes to significantly diminished tremor. My PD symptoms aren't being driven by what otherwise would be chronic anxiety.