I started Alpha Lipoic Acid 600mg daily, back in August and I have had what I consider "tremendous results" from it. As Mrs. D. said, the only side effect I have noticed is occasional heartburn that might last 5-10 minutes. I can usually prevent it by taking it with a meal or milk. The only other thing I have noticed is a slight smell to my urine (sorry if that is TMI) right after I take the dose. Since starting the ALA I have cut down from 2400mg of Neurontin per day to 300 mg at night. I also take Tramadol 50 mg maybe 2 or 3 times a week. That's it. I feel really blessed and hope that I continue to do well, but if it came back full strength tomorrow I would be grateful for the good days I have had and will pray that the good days will return again someday. I am in a good place now but have been in a really dark place before so I am able to empathize and sympathize. Good luck.......I would give it a try....what do you have to lose? PS once I started taking it, I noticed results in about 10 days with increased improvement over time. Hope this helps.