Hi Sandra -

Lyrica (pregabalin) is serotonin-norepinephrine reuptake inhibitor (SNRI), making it a cousin of sorts to serotonin specific reuptake inhibitors (SSRIs) such as Prozac.

I resisted going from Neurontin to Lyrica for some time because of a bad experience I had on the SSRIs when I was being treated for ADHD. Essentially, they were giving me an excess sense of speediness and insomnia well before they had any therapeutic effect.

I don't know if you have any issues with cramping/spasms - and please forgive me if we have discussed this in the past - but I found that after I had been on the Lyrica for a couple of weeks, the quality of my cramping had changed, and not for the better. It even felt as though I could "taste" a bit of an SSRI in the background. I went back to good/bad old Neurontin and sure enough, the "speediness" in the cramping resolved.

For what it's worth . . . .

Mike