As we all know there are many side effects of our meds. The least of these being GI symptoms. My problems are what I call "partial bowel obstructions". It begins with a small bowel movement-loose. Followed by constipation then alot of diarrhea. This happens maybe 1-2x a month, otherwise I stay pretty regular but more to the side of constipated till the diarrhea hits. All of this is compounded by the fact that it seems that I get little warning-it feels like I've gotta go NOW and then wham. This makes it less than pleasant to go out for the day. I usually ruin at least 2 pair of underwear a month, leading me to use these depends garments. I have tried to deal with this as an IBS issue but I still get little warning. Docs have suggested more vegs, water for regularity, etc. and I know I need to do better but it's very frustrating.