Jim,

I haven't heard of any lower GI side effects of meds. I do know that anticholinergics like Amantadine cause or exacerbated constipation. I am fairly atypical in this area, as in I'd say I'm a little slow but not full blown.

Are these extreme fluctuations happening near med dosages? If not, maybe time to check in with your regular doc, It is easy to think everything is PD related but not always the case. It could be something else that is easily treatable.

Laura