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Old 12-23-2010, 08:29 PM
athena athena is offline
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Join Date: Aug 2010
Posts: 22
10 yr Member
athena athena is offline
Junior Member
 
Join Date: Aug 2010
Posts: 22
10 yr Member
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Quote:
Originally Posted by EE03 View Post
I'm curious to know what your biopsy showed, if you care to share.
Here's an excerpt with the highlights: "The combination of perivascular mononuclear inflammation of small caliber vessels in the endomysium, with concurrent active neurogenic atrophy suggests a probable vasculitic process affecting both nerve and muscle. The most common clinical presentation of this pathological entity is painful asymmetric axonal polyneuropathy or moneuritis multiplex, neither of which is reported clinically. The findings do not support a metabolic myopathy or a glycogen storage disorder. These findings could also represent a low-grade autoimmune disorder or vasculitis associated with a paraneoplastic syndrome." Also, "there is nonselective fiber atrophy. Immunohistochemical studies for CD3, CD8 and CD163 highlight T-cell rich perivascular infiltrates in the endomysial vessels, as well as surrounding myophagocytic cells and perivascular histiocytes."

No antibodies for connective tissue diseases or paraneoplastic antibodies are showing up in my serum. I had a chest CT today to look for masses. If that's negative I see a neurologist to repeat the EMG and NCV and will have another muscle biopsy since my disease has progressed since the first biopsy in the spring with pain, tingling, and burning now in addition to the weakness.

Athena
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