I too had shingles, but long after MS dx. Mine was probably activates by taking a chemo drugs called Hydroxy-urea (Hydrea) for my third disease, Polycythemia Vera. The Hydrea
was to knock down the number of platelets in my blood. I got very bad shingles, hip to foot, and was in the hospital with it and took six weeks to walk again without a walker. Valtrex was a good drug to knock it out, but still I needed the six weeks to relearn walking.

I don't know what relationship it might have to MS in me.

I am now trying Interferon in low dose to try to deal with the high platelets. It too
has side effects but so far not as bad as Hydrea. I am unclear how it works, it does affect immune system but probably selectively, i.e., lowering some immunity and raising other. It does not seem to cause marked neuro symptoms--unless burning skin is a parasthesia or chills is a neuro symptom...these go away after an hour or so, usually attacking in the middle of the night. I have to give myself a shot tomorrow because I can't go to the clinic, being snowed in.