Took both medications at one time. I was up to 2700 mg of gabapentin a day. It did not make me sleepy after the first few days, and it did help some with the burning pain I was experiencing, but I was increasing my dose every six months. I was also experiencing some selling in my ankles, and gained about 15 pounds. I did not want to increase the dose again so under my doctor's supervision I tapered off of it. In retrospection, I probably tapered off of it to quickly I had been on gabapentin for over two years. The taper was pretty horrible -- constant nausea and dizziness (took me about 3 weeks). It then took about one more month after I was completely off of it to feel better. I definitely would not stop it cold turkey.

I was taking 60 mg of baclofen when I tapered off of it. It never really help my spasticity. this taper was much easier. I also tried tiznatidine for my spasticity. and it was helping a bit at a rather low dose, but It caused me to have extreme nausea.