Azilect is not an agonist. It is an MAOB inhibitor. In a nutshell it has a chance of slowing down the progression of the PD. It is not meant to really treat the symptoms though my husband says he finds he has a little bit better function in his weak hand a couple hours after he takes it.

I STRONGLY reccomend you research these medicines before getting on them so you know what is going on in your body. Its really all we DO have control over

As for the depression, Azilect used to be used as an anti-depressant. However, PD can cause clinical depression so you should talk to your doctor about it. I do not know what other meds you are on or you personally so I wouldn't assume what is causing this.

Sending warth thoughts your way