Hey i am new to this and would really appreciate any insight... I currently have asthma , graves disease , and reflux. One year ago i began having problems climbing stairs - my legs would be too weak as i got near the top and i would swing my hips to complete the climb. My endo tested thyroid and all ok, but ana was 1:320 speckled & homogenous. I was sent to rheumy (lupus ?), once again positive ana but normal crp,esr,..second rheumy visit with another doctor but nothing again. Lumbar spine mri showed degeneration but no compressions accounting for leg weakness. By the time i was seen by neuro , my legs were constantly tight and i could not walk inclines of any sort, some days i could not walk level ground without swinging hips. Neuro tested me for myasthenia gravis and b12. Testing all ok. I asked for thoracic mri due to numb area between shoulders. Mri showed cystic areas in mediastinum but spine ok. Nct and emg ok. I asked for mri head and neck, neuro dismissed idea. Pcp did mri of head and neck , both ok. Second neuro doc -2 mos later -has sent me to physical therapy where therapist states my legs are spastic and right leg rigid. Also, arms show weakness and tightness at inner elbows. Stretching exercises being done. Evoked potential 1 week ago negative but my back was too tight-per technician- so she bypassed that area and picked up testing at cervical area ? Currently my uvula is leaning toward the right, my vocal cords do not fully close (hoarse all the time) - per ent and laryngo scope - and food is not moving through esophagus thoroughly-per ent and barium study. Two weeks ago my eyes hurt, and my eyelids drooped for about one week . I had difficulty keeping my eyes open in the light. Where do i go from here ? Is ms completely ruled out ? Thanks for any help.