".....Degeneration of dopaminergic neurons was accompanied by progressive protein aggregate formation and functional motor deficits AND WAS PARTIALLY RESCUED BY A-SYNUCLEIN...."

This sounds to me like a-synuclein is protective rather than causative...in which case therapies, including Affiris' PD vaccine they are working on (which I understand keeps a-synuclein plaques from forming and/or busts them up?) would make things worse, not better? Tell me it isn't so.