Thread: Glutathione depletion and overproduction both initiate degeneration of nigral dopamin
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Old 01-04-2011, 07:02 PM
paula_w paula_w is offline
In Remembrance
  
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
paula_w paula_w is offline
In Remembrance
 
Join Date: Aug 2006
Location: Florida
Posts: 3,904
15 yr Member
Default don't know
Quote:
Originally Posted by lurkingforacure View Post
".....Degeneration of dopaminergic neurons was accompanied by progressive protein aggregate formation and functional motor deficits AND WAS PARTIALLY RESCUED BY A-SYNUCLEIN...."

This sounds to me like a-synuclein is protective rather than causative...in which case therapies, including Affiris' PD vaccine they are working on (which I understand keeps a-synuclein plaques from forming and/or busts them up?) would make things worse, not better? Tell me it isn't so.
I'm hoping they know something we do not because I can't understand how they can block something when they don't know it's function in the first place.
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paula

"Time is not neutral for those who have pd or for those who will get it."
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