500mg a day of Ester C should be enough.
The B's go down better with food, as some people get heart burn from them. (but not everyone). You can take the Ester C with food too. Anytime in the early day is fine for both of these.
If you take them at night you may wake up having to go the the bathroom to urinate...water soluble vitamins come out thru the urine. Also the B's are energizing for some people, so early in the day is best. Taking Vitamins at night may contribute to reflux also.
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Weezie looking at petunias 8.25.2017
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