Hello MG NeuroTalk Group.

Well...my neurological mystery journey may have started in 2007 but erupted in November 2008. I haven't had one symptom that has been consistent with the exception of diffuse muscle twitching (i.e., fasciculations). I've had buzzing in my legs, tingling all over at different times, muscles aches in legs/back/neck/feet, ripping headaches, extreme tightness in my chest, and most recently some swallowing issues and mild ptosis (drooping) on my left eye. Occasionally I'll experience weakness in my arms, like when I'm in the garden using the hedge cutters my arms will feel tired but resume temporary strength after resting them. My most recent issue is swallowing problems that create a sensation that food is going up my nose when I swallow, but because it waxes and wanes, the last time my ENT scoped my nose to look at my swallowing function (last week), he didn't see anything abnormal. Also, I've been dealing with neck and shoulder pain (soreness), and I wake up in the morning with achy toes (yes, I know, it sounds strange).

Over the last two years I've had three independent EMGs, MRIs (C-spine, L-spine, chest), x-rays (chest), modified and regular barium swallow tests, two nasal scopes, lung function test, endoscopy, and countless blood tests. All of these have revealed nothing! I've seen two neurologists and both can't find anything abnormal, which is wonderful but it doesn't help explain my condition. The differential diagnoses that I've been given include: benign cramp fasciculation syndrome, toxicity exposure (possibly ciguatera), or anxiety. The benign cramp fasciculation dx could very well be what I'm experiencing, but it doesn't explain the swallowing issue or the mild ptosis that I'm experiencing. One of my neuros said it's not MS because I wouldn't have diffuse fasciculations. Another neuro said it's most likely not ALS because I had three clean EMGs and I'm not showing progressive weakness.

Any advice? Does what I've describe sound remotely like MG? Are there other tests I should request from my neurologist?

Thanks in advance for your help!